Endocrine Abstracts

Background: Vitamin D is a growing endemic problem. Wide proportions of healthy adults are deficient in vitamin D. It is very important for skeletal and non-skeletal health. It is now well established that many people have vitamin D levels that are less than currently recommended for optimal healthAim of this work: To assess vitamin-D sufficiency/deficiency in a sample of healthy Egyptian adult males in Dakahlia Governorate in Northern Egypt and correlat...

Background: Hyperglycaemia produces various changes in the vascular tissue at the cellular level that accelerates the atherosclerosis. There is a direct correlation among carotid arterial stiffness and serum fetuin-A level. Fetuin-A is a marker of the inflammatory nutritional state and acts as a protective agent because it solubilises the calcium phosphate salt.Aim of this work: To study the role of fetuin A in atherosclerosis and its association with ty...

Background: Diabetes is a risk factor for both PAD and PAD-associated mortality. Diabetic patients have worse arterial disease and a poorer outcome than nondiabetic patients. Fetuins are blood proteins made in the liver more abundant in fetal blood. Fetuin-A is regarded as an inhibitor of systemic calcification.Aim of this work: To assess the relationship between plasma fetuin-A levels and peripheral vascular disease in type 2 diabetes mellitus.<p cl...

Background: In polycystic ovary syndrome (PCOS), insulin resistance (IR) might be involved in the development of endocrine and metabolic abnormalities. Visfatin, a protein secreted by adipose tissue, is suggested to play a role in pathogenesis of insulin resistance. However, the biological activity and regulation of this novel adipokine are still unknown.Objectives: To study the visfatin level in PCOS in Egyptian women and its relationship with IR and ma...

Background: TSH secretion shows a diurnal rhythm with a surge in the evening. The nocturnal surge is essential for thyroid function regulation. TSH surge is suggested to be blunted in central hypothyroidism. In idiopathic short stature (ISS), thyroid dysfunction has been suggested ranging from mild hypothyroidism to central hypothyroidism.Aim of the work: To study the pituitary thyroid axis and the TSH surge in ISS.Materials and me...